国家自然科学基金项目81570290、81600264;上海市科委科研计划项目15411952600;上海申康医院发展中心促进市级医院临床技能与临床创新三年行动计划16CR3087B;上海青年医师培养资助计划 National Natural Science Foundation of China81570290、81600264;Shanghai Science and Technology Grant15411952600;Shanghai Shenkang Hospital Development Center Grant16CR3087B;Shanghai Young Physician Training Program