国家自然科学基金81771266;上海市申康三年行动计划重大临床研究项目SHDC2020CR4037;长海医院234学科攀峰计划2020YXK033;National Natural Science Foundation of China81771266;Shanghai Shenkang Three-year Action Plan Major Clinical Research ProjectSHDC2020CR4037;234 Discipline Peak Climbing Program of Changhai Hospital2020YXK033