国家临床重点专科建设项目国卫办医函[2013]544号;国家自然科学基金81671286;重庆市教委科学技术研究项目KJ1702011National Key Clinical Specialties Construction Program of China[2013]544;the National Natural Science Foundation of China81671286;Scientific and Technological Research Program of Chongqing Municipal Education CommissionKJ1702011