国家重点研发计划2017YFC0909900;青海省科技厅项目2017-SF-L2;青海省卫生计生委重点课题2016-wjzd-04National Key R&D Program of China2017YFC09900;Project of Qinghai Provincial Science and Technology Department2017-SF-L2;Key Project of Qinghai Province Health and Family Planning Commission2016-wjzd-04