国家自然科学基金81571422;南方医科大学南方医院临床研究专项2018CR030;广东省教育厅高水平大学建设经费南方医科大学临床研究启动项目LC2016ZD019;National Natural Science Foundation of China81571422;Special Program of Clinical Research of Nanfang Hospital, Southern Medical University2018CR030;Clinical Research Startup Program of Southern Medical University by High-level University Construction Fund of Department of Education of Guangdong ProvinceLC2016ZD019