Deciphering the metabolic fates of herbal constituents and the interactions of herbs with human metabolic system
Herbal medicines play a crucial role in the healthcare system in China and other East Asian countries,and also have been used as altemative medicines in most Westem countries ”1-3”.However,in most cases,the metabolic fates of herbal constituents and their effects on drug metabolism or endogenous metabolism in the human body have not been well-investigated ”4-5”.Notably,the concomitant use of herbal medicines may lead to clinically relevant herb-drug interactions or adverse reactions or even metabolic disorders,when some herbs are co-administrated with those drugs with narrow therapeutic indices (e.g.warfarin,digoxin,thyroid hormones and some anticancer agents) ”6-8”.
adverse reactions、human body
17
R
the National Key Research and Development Program of China 2017YFC1700200
2020-01-13(万方平台首次上网日期,不代表论文的发表时间)
共2页
801-802