国家自然科学基金51308132;广东省科技计划2014A050503063,2015B020235013;广州市科技计划项目No.201510010033,2016201604030058 Supported by the National Natural Science Foundation of China51308132;the Science and Technology Planning Project of Guangdong Province2014A050503063,2015B020235013;the Scientific and Technological Planning Project of Guangzhou201510010033,2016201604030058