国家科技重大专项No.2014ZX07206-005-04;国家自然科学基金No.41401115;广东省科技计划No.2014A020216017Supported by the National Science and Technology Major Project No.2014ZX07206-005-04,the National Natural Science Foundation of ChinaNo.41401115 and the Science and Technology Planning Project of Guangdong Province,China No.2014A020216017