上海市市级医院新兴前沿技术联合攻关项目SHDC12010115,上海市自然科学基金11ZR1447800,军队临床高新技术重大项目2010gxjs057,上海市重点学科项目.Supported by the Municipal Hospitals' Project for Emerging and Frontier Technology of Shanghai SHDC12010115,Natural Science Foundation of Shanghai 11ZR1447800,PLA Major Project for Clinical High-tech and Innovative Technology2010gxjs057,and Project for the Key Discipline of Shanghai.